Research Scientist, Neurodegenerative Diseases
Location Type: On-site
Job Number: 2400003Z
Category: Research & Laboratory
Job Number: 2400003Z
Category: Research & Laboratory
The Department of Neurology is seeking a Research Scientist to work on a research project that is focused on investigating mechanisms of neurodegeneration utilizing various cell culture and mouse models. The position requires a PhD or MD/PhD and experience utilizing mammalian cell culture models and/or mouse models. Preference will be given to candidates demonstrating expertise in iPSC neuronal differentiation protocols or establishing in vitro neuronal cell cultures from mouse models. Ideal candidates would have previous experience in researching mechanisms of neurologic disease in an academic medical center or healthcare setting.
· The ability to culture and maintain induced pluripotent stem cell lines is preferred.
· Experience in design and implementation of genome editing techniques, including CRISPR/Cas9 platforms, is preferred.
· Experienced and independent in molecular biology techniques, including nucleic acid extraction and quantification, PCR, RT-qPCR, agarose gel electrophoresis, protein extraction and quantification, Western blot, immunostaining/microscopy.
· Experience working with neuronal cultures established from mouse models is preferred.
· Demonstrated experience working effectively as a member of a team and independently.
· Excellent communication, organizational, and record-keeping skills.
· Demonstrate a proactive and goal-oriented work ethic.
· Ph.D. degree with major coursework in field of assignment and five (5) years research experience in field of assignment, including at least two (2) years at level of Senior Research Associate or equivalent. or
· Master’s degree with major coursework in field of assignment and seven (7) years research experience in field of assignment, including at least three (3) years at level of Senior Research Associate or equivalent. or
· Bachelor’s degree with major coursework in field of assignment and nine (9) years research experience in field of assignment, including at least four (4) years at level of Senior Research Associate or equivalent.
· Plans, organizes, coordinates, directs, and personally participates in assigned scientific or medical research projects. Selects or assists in selection of key research personnel. Determines specific goals or objectives to be attained and assigns and reviews work of subordinates. Plans experimental protocols.
· Reviews and analyzes resulting research data. Revises techniques or approaches to work problems as indicated necessary by research data.
· Compiles, writes, and submits research results to supervisor. Prepares or assists in preparation of research papers, reports, and abstracts for publication as one of co-authors.
· Designs, develops, or adapts equipment used in experiments or research to obtain desired results.
· Plans and supervises training of technicians and other laboratory personnel with respect to proper laboratory techniques, use of laboratory equipment, and safety procedures.
· May confer with industrial, governmental, or other groups concerning progress or results of research project.
· Performs other duties as assigned.
To learn more about the benefits UT Southwestern offers, visit https://www.utsouthwestern.edu/employees/hr-resources/
This position is security-sensitive and subject to Texas Education Code §51.215, which authorizes UT Southwestern to obtain criminal history record information. UT Southwestern Medical Center is committed to an educational and working environment that provides equal opportunity to all members of the University community. As an equal opportunity employer, UT Southwestern prohibits unlawful discrimination, including discrimination on the basis of race, color, religion, national origin, sex, sexual orientation, gender identity, gender expression, age, disability, genetic information, citizenship status, or veteran status.
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(Eligibility varies by employment status)
Explore the full range of opportunities we offer within our research areas and labs.
If you want a larger canvas for exploration and discovery, look no further. We have more than 500 labs on campus. Here are just a few of the research investigations you’ll find underway at UT Southwestern Medical Center:
Work here, and you’ll help us create and conduct translational bench-to-bedside research that quickly moves basic discoveries into treatments that directly benefit patients. Here’s an example: We’ve found that small artificial molecules called peptoids show promise as both diagnostic tools and treatments for various types of cancer. Peptoids can bind to cancerous cells more tightly than normal cells. So our researchers are looking at ways to combine peptoids with anti-cancer drugs to target cancer cells more specifically.
At UT Southwestern, you can be part of our next breakthrough.
As a progressive, innovation-driven medical center, UT Southwestern relies heavily on our lab techs, medical techs, histotechnologists, and cytotechnologists to play a key role in the diagnosis and care planning of patients.
Our broad spectrum of services will present you with opportunities to work across a range of dynamic lab settings. You’ll have abundant tools, training, and support to facilitate your success and professional growth.
For each member of this diverse and collaborative team, we provide excellent benefits, including PTO and pension and retirement plans. When you consider Dallas’ relatively low cost of living and high quality of life, UT Southwestern emerges as your best option for a fulfilling career.
There are many ways to contribute here. As we continue to explore new solutions that will save lives and enhance quality of life for millions, we’re committed to providing rigorous scientific training in both basic and clinical research to scholars across the Medical Center and community. You can take advantage or help support a number of robust programs, such as:
Fellowship Program (QP-SURF)
Our research teams help plan, conduct, fund, administer, and report on clinical trials across the broad spectrum of health conditions and diseases. More than 1,000 trials are currently underway, including these areas of medicine: