Postdoctoral positions are available in the laboratory of Dr. Srinivas Malladi, Ph.D. – Faculty Profile – UT Southwestern, Department of Pathology at UT Southwestern Medical Center to study metastatic dormancy and recurrences in breast, lung and renal adenocarcinomas. Malladi Lab – UT Southwestern, Dallas, Texas is focused on developing improved diagnostic and therapeutic modalities for treating residual disease and metastasis. We employ molecular, biochemical, immunologic, genomic, imaging and computational based techniques to understand the biology of latent and overt metastasis in breast and kidney cancers using mouse models, xenografts and patient samples. 

Recent Publications: 

Metabolic adaptations of brain metastasis. Nature Reviews Cancer, 2025.

AXL/WRNIP1 mediates replication stress response and promotes therapy resistance and metachronous metastasis in HER2+ breast cancer. Cancer Research, 2024.

Limiting mitochondrial plasticity by targeting DRP1 induces metabolic reprogramming and reduces breast cancer brain metastases. Nature Cancer, 2023.

Cell competition shapes metastatic latency and relapse. Cancer Discovery, 2023.

Metabolic diversity within breast cancer brain-tropic cells determines metastatic fitness. Cell Metabolism, 2022.

Candidates must hold a recent Ph.D. and/or M.D. degree. Prior research experience with Cancer biology, mouse models, organoids, epigenetics, CRISPR screens, microscopy and bioinformatics will be highly regarded. A track record of productivity and publications in peer-reviewed journals is essential.

Information on our postdoctoral training program, benefits, and a virtual tour can be found at http://www.utsouthwestern.edu/postdocs

Interested individuals should send a CV and statement of interest to:                                                                                                Srinivas Malladi, Ph.D.                                                                                                                                                                        UT Southwestern Medical Center                                                                                                                                                        5323 Harry Hines Blvd.                                                                                                                                                                        Dallas, TX 75390-9072                                                                                                                                                                        Srinivas.Malladi@utsouthwestern.edu                                                                                                                                        https://labs.utsouthwestern.edu/malladi-lab                                                    https://profiles.utsouthwestern.edu/profile/173686/srinivas-malladi.html

Interested individuals must upload a CV, cover letter, and a list of three references.

UT Southwestern Medical Center is committed to an educational and working environment that provides equal opportunity to all members of the University community.  As an equal opportunity employer, UT Southwestern prohibits unlawful discrimination, including discrimination on the basis of race, color, religion, national origin, sex, sexual orientation, gender identity, gender expression, age, disability, genetic information, citizenship status, or veteran status.

This position is security-sensitive and subject to Texas Education Code 51.215, which authorizes UT Southwestern to obtain criminal history record information.

Appointment rank will be commensurate with academic accomplishment and experience. Consideration may be given to applicants seeking less than a full-time schedule.

To learn more about the benefits UT Southwestern offers, visit https://www.utsouthwestern.edu/employees/hr-resources/