Instructor – Structural Biology – Bai Lab
Location: Dallas, TX
Location Type:
Location Type:
Job Number: 938768
Category: Faculty and Physicians
23331871
Responsibilities
An Instructor position is available in the laboratory of Dr. Xiaochen Bai, Associate Professor in the Department of Biophysics at UT Southwestern Medical Center. The Instructor will lead advanced research efforts under the strategic direction of the lab, contributing to its overarching scientific mission. The Bai lab focuses on the structural and functional analysis of receptor tyrosine kinases (RTKs), with the goal of understanding how distinct RTKs utilize receptor-specific mechanisms to initiate and regulate signal transduction.
The Instructor will investigate the apo and active conformations of the insulin receptor in complex with regulatory factors using single-particle cryo-electron microscopy (cryo-EM). Following structural characterization, the role of these regulatory factors in insulin receptor signaling will be examined through structure-guided mutagenesis.
Core responsibilities include recombinant protein expression and purification, cryo-EM data collection and structure determination, atomic model building, and cell-based functional assays. The Instructor is expected to work collaboratively within a multidisciplinary environment and contribute to experimental design, data acquisition, analysis, and interpretation to advance innovative discoveries in the lab.
This position requires extensive experience in protein biochemistry, as well as structural and functional analysis of proteins involved in signal transduction. The ideal candidate will hold a Ph.D. in biochemistry, structural biology, or a closely related field.
Applicants should apply online and upload a current CV.
UT Southwestern Medical Center is committed to an educational and working environment that provides equal opportunity to all members of the University community. As an equal opportunity employer, UT Southwestern prohibits unlawful discrimination, including discrimination on the basis of race, color, religion, national origin, sex, sexual orientation, gender identity, gender expression, age, disability, genetic information, citizenship status, or veteran status.
This position is security-sensitive and subject to Texas Education Code 51.215, which authorizes UT Southwestern to obtain criminal history record information.
Appointment rank will be commensurate with academic accomplishment and experience. Consideration may be given to applicants seeking less than a full-time schedule.
To learn more about the benefits UT Southwestern offers, visit https://www.utsouthwestern.edu/employees/hr-resources/
Benefits
- UT Southwestern is proud to offer a competitive and comprehensive benefits package to eligible employees. Our benefits are designed to support your overall wellbeing, and include:
- PPO medical plan, available day one at no cost for full-time employee-only coverage
- 100% coverage for preventive healthcare – no copay
- Paid Time Off, available day one
- Retirement Programs through the Teacher Retirement System of Texas (TRS)
- Paid Parental Leave Benefit
- Wellness programs
- Tuition Reimbursement
- Public Service Loan Forgiveness (PSLF) Qualified Employer
- Learn more about these and other UTSW employee benefits!
Benefits
Benefits
- UT Southwestern is proud to offer a competitive and comprehensive benefits package to eligible employees. Our benefits are designed to support your overall wellbeing, and include:
- PPO medical plan, available day one at no cost for full-time employee-only coverage
- 100% coverage for preventive healthcare – no copay
- Paid Time Off, available day one
- Retirement Programs through the Teacher Retirement System of Texas (TRS)
- Paid Parental Leave Benefit
- Wellness programs
- Tuition Reimbursement
- Public Service Loan Forgiveness (PSLF) Qualified Employer
- Learn more about these and other UTSW employee benefits!
Working at UTSW
Bring Your “A” Game.
Why are top candidates in so many professional fields – including customer service, finance, and human resources, to name a few – choosing UT Southwestern Medical Center as a career home? Simple. They know that they will work among a team of people who bring their best every day to support a health organization that’s breaking new ground in dozens of ways. That’s what we can offer you.
It takes a lot to keep UT Southwestern at the forefront, where world-class patient care, acclaimed medical education, and innovative research breakthroughs are common occurrences. When you join us, those are the challenges you’ll share. Our organization has taken on serious commitments and responsibilities within a rapidly evolving health care system.
Change is a constant, so our work supporting this complex matrix of business and systems needs must rise to the highest level of professionalism, collaboration, and innovation. That’s true for every role across the Medical Center and represents why this can be the most challenging work of your career.
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Employee Testimonials
Vanessa Pantoja
Vanessa Pantoja
GME Program Coordinator
GME Program Coordinator
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Brenda Edwards.
Brenda Edwards
Licensed Clinical Social Worker
Licensed Clinical Social Worker
UT Southwestern is a great place to work and learn. Innovation and creativity to improve the quality of patient care are encouraged. Leadership within my team and department is supportive.
Denise Anderson
Denise Anderson
GME Coordinator I
GME Coordinator I
I love working at UT Southwestern because of its great staff and great benefits. Everyday is extraordinary because there’s opportunity to expand your knowledge and advance your career.
