Position Overview

The Choi Laboratory is seeking a highly motivated and collaborative postdoctoral researcher to help develop the next generation of cancer immunotherapies. Our research integrates cancer immunology, T-cell and protein engineering, and translational science to uncover mechanisms of immune regulation and convert those discoveries into rationally designed therapies.

The successful candidate will join the Center for Cellular Therapies and Cancer Immunology and work alongside basic scientists, translational researchers, and clinicians with expertise in immunology, cancer biology, molecular engineering, and therapeutic development. Projects are designed to progress from mechanistic discovery through preclinical development, providing exposure to programs moving toward first-in-human studies. This position is particularly well suited for researchers seeking rigorous scientific training and preparation for careers in academia, biotechnology, or translational medicine.

Research Focus

The successful candidate will investigate and engineer immune responses in cancer, with particular emphasis on:

• T-cell engineering
• Cancer immunology and immunotherapy
• Protein and cell engineering for next-generation immunotherapies

Why Join the Choi Laboratory at UT Southwestern?

UT Southwestern Medical Center is an internationally recognized academic medical center where scientists and clinicians work together to translate discovery into better treatments. Through the Choi Laboratory’s affiliations with the Center for Cellular Therapies and Cancer Immunology and the Harold C. Simmons Comprehensive Cancer Center, postdoctoral researchers have access to multidisciplinary expertise, advanced shared core facilities, extensive institutional research support, and opportunities to connect laboratory discoveries with unmet clinical needs.

The Harold C. Simmons Comprehensive Cancer Center is an NCI-designated Comprehensive Cancer Center recognized for excellence across basic, clinical, prevention, and population-based cancer research. This highly collaborative environment allows postdoctoral researchers to engage with scientists and clinicians across traditional disciplinary boundaries while developing the technical, scientific, and professional skills needed for their next career stage.

Postdoctoral researchers receive a competitive salary and comprehensive benefits, individualized mentoring, and access to institutional career-development resources. Located in Dallas, UT Southwestern combines the resources and scientific community of a major academic medical center with the professional and cultural opportunities of one of the country’s largest and most diverse metropolitan areas.

Candidates must hold a recent Ph.D. in Immunotherapy, Molecular Biology, or a related field.  Experience in cellular and molecular biology techniques.  Candidates must also have experience with flow cytometry and immunological techniques leading to publication in peer-reviewed journals is recommended.

Preferred Qualifications include experience with mouse models, familiarity with next-generation sequencing analysis, a background in T cell biology or cancer immunology, and programming skills (R, Python) for data analysis.

Please read recent manuscripts published in the last two years.

Applicants should apply at https://jobs.utsouthwestern.edu/Search for Job # 956910

Information on our postdoctoral training program, benefits, and a virtual tour can be found at htt;s://www.utsouthwestern.edu/postdocs

UT Southwestern Medical Center is committed to an educational and working environment that provides equal opportunity to all members of the University community.  As an equal opportunity employer, UT Southwestern prohibits unlawful discrimination, including discrimination on the basis of race, color, religion, national origin, sex, sexual orientation, gender identity, gender expression, age, disability, genetic information, citizenship status, or veteran status.

This position is security-sensitive and subject to Texas Education Code 51.215, which authorizes UT Southwestern to obtain criminal history record information.

Appointment rank will be commensurate with academic accomplishment and experience. Consideration may be given to applicants seeking less than a full-time schedule.

To learn more about the benefits UT Southwestern offers, visit https://www.utsouthwestern.edu/employees/hr-resources/