POSTDOCTORAL RESEARCHER – Ophthalmology – Harbour Lab
Location Type:
Job Number: 984910
Category: PostDoc
Job Number: 984910
Category: PostDoc
A postdoctoral research position is available in the Department of Ophthalmology at UT Southwestern Medical Center.
The postdoctoral fellow will study genomic evolution, immune evasion, and metastasis in uveal melanoma, a highly metastatic cancer of the eye. Our laboratory has discovered multiple genomic aberrations associated with metastasis in uveal melanoma, including bi-allelic mutational inactivation of the tumor suppressor BAP1, hemizygous change-of-function mutations in the splicing factor SF3B1, and aberrant expression of the cancer-testis antigen PRAME. We use a variety of techniques in cell biology, biochemistry, genetics, genomics, and epigenetics to elucidate how these aberrations interact with the tumor microenvironment to promote immune evasion and metastasis. The training experience will include the use of next generation sequencing methods such as RNA-seq, ChIP-seq, ATAC-seq, scRNA-seq, and spatial transcriptomics, as well as cell culture and genetically engineered mouse models.
Ph.D. with major coursework in the field of assignment, no experience required, and less than six (6) years of postdoctoral research experience
Applicants must submit a CV, a cover letter, and a list of three references.
UT Southwestern Medical Center is committed to an educational and working environment that provides equal opportunity to all members of the University community. As an equal opportunity employer, UT Southwestern prohibits unlawful discrimination, including discrimination on the basis of race, color, religion, national origin, sex, sexual orientation, gender identity, gender expression, age, disability, genetic information, citizenship status, or veteran status.
This position is security-sensitive and subject to Texas Education Code 51.215, which authorizes UT Southwestern to obtain criminal history record information.
Appointment rank will be commensurate with academic accomplishment and experience. Consideration may be given to applicants seeking less than a full-time schedule.
To learn more about the benefits UT Southwestern offers, visit https://www.utsouthwestern.edu/employees/hr-resources/
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