A postdoctoral training position is available in the laboratory of Dr. Benjamin Levi, in the Center for Organogenesis and Trauma, Children’s Research Institute and Center for Mineral Researcher at the University of Texas Southwestern Medical Center. The Postdoctoral Researcher would be joining a basic and translational laboratory funded by the NIH and DOD that consists of post-doctoral fellows, medical students, technicians and a research scientist supervised by Dr. Benjamin Levi.

Research Focus

The Levi Lab investigates how cellular plasticity, inflammatory signaling, and tissue microenvironments influence disease outcomes following injury and in cancer. Ongoing cancer-focused projects investigate mechanisms underlying osteosarcoma and related musculoskeletal malignancies, including:

· How tumor–stromal and tumor–immune interactions shape cancer cell fate

· The role of nerves and on tumor progression

· Shared molecular pathways between regeneration, fibrosis, and oncogenesis

· Identification of therapeutic vulnerabilities within the tumor microenvironment

This work integrates cancer biology, developmental and regenerative pathways, immunology, and in vivo disease models, with direct relevance to patient outcomes. This position is ideal for a scientist interested in applying modern cancer biology approaches to clinically relevant, understudied tumor contexts at the intersection of oncology and tissue biology.

Preferred Experience

· Bone, soft tissue, or sarcoma biology

· Tumor microenvironment, stromal biology, or cancer-associated inflammation

· In vivo cancer models

· Single-cell, spatial, or multi-omic profiling

· Translational or clinically motivated oncology research

This research integrates developmental biology, regenerative medicine, and immunology providing postdoctoral fellows with a rare opportunity to connect fundamental musculoskeletal biology to clinically relevant outcomes.

Training Environment

The Levi Laboratory is a well-funded (NIH and DoD), highly collaborative basic and translational research group composed of postdoctoral fellows, clinician-scientists, medical students, technicians, and research scientists. Postdoctoral fellows are encouraged to drive independent cancer-focused projects, develop interdisciplinary collaborations, and lead first-author publications.

The training environment emphasizes:

· Mechanistic, hypothesis-driven cancer biology

· Strong mentorship with increasing scientific independence

· Exposure to translational and clinically informed research questions

· Active support for academic, industry, and translational career paths

Vision of the Levi Laboratory: Enhance the human experience.

Mission of Levi Laboratory: Maintain a culture of collaboration, connection, rigor and wellness to support ground-breaking research using state of the art techniques and technologies to help those afflicted by injuries and diseases of the skin and musculoskeletal systems.

Candidates must hold a Ph.D. in Cancer biology, Immunology, Cellular and Molecular Biology, Biochemistry, Genetics or other relevant branches of biological sciences. Experience in immunology, animal handling and surgery, single cell sequencing, molecular and cell biology, matrix biology, histologic analyses and flow cytometry leading to publication in peer-reviewed journals is recommended.

Interested individuals should apply and upload a CV, a brief statement of interests in a cover letter, and a list of three references.

UT Southwestern Medical Center is committed to an educational and working environment that provides equal opportunity to all members of the University community.  As an equal opportunity employer, UT Southwestern prohibits unlawful discrimination, including discrimination on the basis of race, color, religion, national origin, sex, sexual orientation, gender identity, gender expression, age, disability, genetic information, citizenship status, or veteran status.

This position is security-sensitive and subject to Texas Education Code 51.215, which authorizes UT Southwestern to obtain criminal history record information.

Appointment rank will be commensurate with academic accomplishment and experience. Consideration may be given to applicants seeking less than a full-time schedule.

To learn more about the benefits UT Southwestern offers, visit https://www.utsouthwestern.edu/employees/hr-resources/